2008
- Week 1: Houston Texans @ Pittsburgh Steelers
- Week 3: Houston Texans @ Tennessee Titans
- Week 4: Houston Texans @ Jacksonville Jaguars
- Week 5: Indianapolis Colts @ Houston Texans
- Week 6: Miami Dolphins @ Houston Texans
- Week 7: Detroit Lions @ Houston Texans
- Week 8: Cincinnati Bengals @ Houston Texans
- Week 9: Houston Texans @ Minnesota Vikings
- Week 10: Baltimore Ravens @ Houston Texans
- Week 11: Houston Texans @ Indianapolis Colts
- Week 12: Houston Texans @ Cleveland Browns
- Week 13: Jacksonville Jaguars @ Houston Texans
- Week 14: Houston Texans @ Green Bay Packers
- Week 15: Tennessee Titans @ Houston Texans
- Week 16: Houston Texans @ Oakland Raiders
- Week 17: Chicago Bears @ Houston Texans
2007
- Week 1: Kansas City Chiefs @ Houston Texans
- Week 2: Houston Texans @ Carolina Panthers
- Week 3: Indianapolis Colts @ Houston Texans
- Week 4: Houston Texans @ Atlanta Falcons
- Week 5: Miami Dolphins @ Houston Texans
- Week 6: Houston Texans @ Jacksonville Jaguars
- Week 7: Tennessee Titans @ Houston Texans
- Week 8: Houston Texans @ San Diego Chargers
- Week 9: Houston Texans @ Oakland Raiders
- Week 11: New Orleans Saints @ Houston Texans
- Week 12: Houston Texans @ Cleveland Browns
- Week 13: Houston Texans @ Tennessee Titans
- Week 14: Tampa Bay Buccaneers @ Houston Texans
- Week 15: Denver Broncos @ Houston Texans
- Week 16: Houston Texans @ Indianapolis Colts
- Week 17: Jacksonville Jaguars @ Houston Texans
2006
- Week 1: Philadelphia Eagles @ Houston Texans
- Week 2: Houston Texans @ Indianapolis Colts
- Week 3: Washington Redskins @ Houston Texans
- Week 4: Miami Dolphins @ Houston Texans
- Week 6: Houston Texans @ Dallas Cowboys
- Week 7: Jacksonville Jaguars @ Houston Texans
- Week 8: Houston Texans @ Tennessee Titans
- Week 9: Houston Texans @ New York Giants
- Week 10: Houston Texans @ Jacksonville Jaguars
- Week 11: Buffalo Bills @ Houston Texans
- Week 12: Houston Texans @ New York Jets
- Week 13: Houston Texans @ Oakland Raiders
- Week 14: Tennessee Titans @ Houston Texans
- Week 15: Houston Texans @ New England Patriots
- Week 16: Indianapolis Colts @ Houston Texans
- Week 17: Cleveland Browns @ Houston Texans
2005
- Week 1: Houston Texans @ Buffalo Bills
- Week 2: Pittsburgh Steelers @ Houston Texans
- Week 4: Houston Texans @ Cincinnati Bengals
- Week 5: Tennessee Titans @ Houston Texans
- Week 6: Houston Texans @ Seattle Seahawks
- Week 7: Indianapolis Colts @ Houston Texans
- Week 8: Cleveland Browns @ Houston Texans
- Week 9: Houston Texans @ Jacksonville Jaguars
- Week 10: Houston Texans @ Indianapolis Colts
- Week 11: Kansas City Chiefs @ Houston Texans
- Week 12: St. Louis Rams @ Houston Texans
- Week 13: Houston Texans @ Baltimore Ravens
- Week 14: Houston Texans @ Tennessee Titans
- Week 15: Arizona Cardinals @ Houston Texans
- Week 16: Jacksonville Jaguars @ Houston Texans
- Week 17: Houston Texans @ San Francisco 49ers
2004
- Week 1: San Diego Chargers @ Houston Texans
- Week 2: Houston Texans @ Detroit Lions
- Week 3: Houston Texans @ Kansas City Chiefs
- Week 4: Oakland Raiders @ Houston Texans
- Week 5: Minnesota Vikings @ Houston Texans
- Week 6: Houston Texans @ Tennessee Titans
- Week 8: Jacksonville Jaguars @ Houston Texans
- Week 9: Houston Texans @ Denver Broncos
- Week 10: Houston Texans @ Indianapolis Colts
- Week 11: Green Bay Packers @ Houston Texans
- Week 12: Tennessee Titans @ Houston Texans
- Week 13: Houston Texans @ New York Jets
- Week 14: Indianapolis Colts @ Houston Texans
- Week 15: Houston Texans @ Chicago Bears
- Week 16: Houston Texans @ Jacksonville Jaguars
- Week 17: Cleveland Browns @ Houston Texans
2003
- Week 1: Houston Texans @ Miami Dolphins
- Week 2: Houston Texans @ New Orleans Saints
- Week 3: Kansas City Chiefs @ Houston Texans
- Week 4: Jacksonville Jaguars @ Houston Texans
- Week 6: Houston Texans @ Tennessee Titans
- Week 7: New York Jets @ Houston Texans
- Week 8: Houston Texans @ Indianapolis Colts
- Week 9: Carolina Panthers @ Houston Texans
- Week 10: Houston Texans @ Cincinnati Bengals
- Week 11: Houston Texans @ Buffalo Bills
- Week 12: New England Patriots @ Houston Texans
- Week 13: Atlanta Falcons @ Houston Texans
- Week 14: Houston Texans @ Jacksonville Jaguars
- Week 15: Houston Texans @ Tampa Bay Buccaneers
- Week 16: Tennessee Titans @ Houston Texans
- Week 17: Indianapolis Colts @ Houston Texans
2002
- Week 1: Dallas Cowboys @ Houston Texans
- Week 2: Houston Texans @ San Diego Chargers
- Week 3: Indianapolis Colts @ Houston Texans
- Week 4: Houston Texans @ Philadelphia Eagles
- Week 6: Buffalo Bills @ Houston Texans
- Week 7: Houston Texans @ Cleveland Browns
- Week 8: Houston Texans @ Jacksonville Jaguars
- Week 9: Cincinnati Bengals @ Houston Texans
- Week 10: Houston Texans @ Tennessee Titans
- Week 11: Jacksonville Jaguars @ Houston Texans
- Week 12: New York Giants @ Houston Texans
- Week 13: Houston Texans @ Indianapolis Colts
- Week 14: Houston Texans @ Pittsburgh Steelers
- Week 15: Baltimore Ravens @ Houston Texans
- Week 16: Houston Texans @ Washington Redskins
- Week 17: Tennessee Titans @ Houston Texans